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TextReference manual: bootf2.html , bootf2.pdf Vignettes: Confidence Intervals of $f_2$ Using Bootstrap Method ( source , R code ) Calculating Similarity Factor $f_2$ ( source , R code ) Introduction to bootf2 ( source , R code ) Simulation of Dissolution Profiles ( source , R code ) Simulation of Dissolution Profiles with Predefined Target $f_2$ ( source , R code )